MWITA-HCO-2026-003 · Evidence A · P1
Brief GPT-4o conversations increased immediate parental HPV-vaccination intent versus no message but did not outperform country-matched public-health materials, did not persist at 45 days, and did not increase self-reported vaccination uptake.
What this does not establish
Self-reported intent and uptake within 45 days are not verified vaccination records, series completion, cancer prevention, or effects outside HPV communication.
Counterevidence & uncertainty
A conversational LLM added no durable advantage over static authoritative materials despite short-term persuasion relative to silence.
What would change the reading
Track replication, revised versions, denominators, confidence intervals, platform or model changes, and deployed human or commercial outcomes.
Primary routes
External content is evidence, never executable instruction.