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SRC-63d07db0d86bdde2 · Source record

Nucleotides as an Anti-Aging Supplementation in Older Adults: A Randomized Controlled Trial (TALENTs study)

Advanced Science / original authors · 4 connected claims

D04 · Health, Evidence, Supplements & PeptidesD19 · Measurement, Experimentation & EconomicsD24 · Frontier Science & Wildcards

Canonical route

https://pmc.ncbi.nlm.nih.gov/articles/PMC12412603/

Claims connected to this source

  1. MWITA-LD-2026-011China's TALENTs trial randomized 121 adults aged 60–70 to 1.2 grams per day of nucleotides or placebo for 19 weeks.Evidence A
  2. MWITA-LD-2026-012TALENTs reported a 3.08-year greater reduction in median DNA-methylation age versus placebo at 19 weeks.Evidence A
  3. MWITA-LD-2026-013TALENTs found no significant between-group change in leukocyte telomere length at either 11 or 19 weeks.Evidence A
  4. MWITA-LD-2026-014TALENTs reported improved HOMA-IR but no severe adverse events during the 19-week study.Evidence A

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